Time to Stop Helicobacter pylori, no Matter with Antibiotic, Probiotic or Vaccine
نویسنده
چکیده مقاله:
To get rid of problematic reports of H. pylori colonization, clinicians’ optimal goal should be to totally bacterial elimination from clinical and environmental samples.
منابع مشابه
Vaccine development against infection with Helicobacter pylori.
Infection with Helicobacter pylori, is one of the most prevalent infections world-wide, where approximately 50% of adults in the developed world and over 90% of inhabitants in the developing world are infected. Chronic infection with H. pylori is the cause of gastritis, peptic ulcer disease and is a risk factor for gastric adenocarcinoma. Recent studies have demonstrated the suitability of an i...
متن کاملAntibiotic susceptibilities of Helicobacter pylori.
OBJECTIVE The aim of this study was to evaluate the prevalence of resistance among 83 Helicobacter pylori isolates cultured from biopsies taken during routine endoscopies in 1998-1999. METHODS Minimum Inhibitory Concentration of amoxicillin, tetracycline, clarithromycin and metronidazole were determined by Epsilometer test. RESULTS Forty-seven strains (57%) were resistant to metronidazole, ...
متن کاملAntibiotic resistance in Helicobacter pylori infection.
Resistance to antibiotics is considered as the primary reason for failure of eradication therapies. Resistance to clarithromycin is due to a decrease in binding to the ribosomes associated with a point mutation on the 23S rRNA. Its rate in Europe varies from 0-15%, with 5% in the UK. The resistance influences dramatically the success of the treatments. Resistance to metronidazole is due to a la...
متن کاملRegional Antibiotic Resistance of Helicobacter pylori
Antibiotic resistance is considered the cause of unsuccessful eradication of Helicobactor pylori (H. pylori) infections. Awareness of regional resistance rates of H. pylori isolates can improve not only empiric antibiotic therapy but also lead to the development of second line treatment and rescue regimens. At present, the most common treatment is empiric eradication. Global regional regimen th...
متن کاملHelicobacter pylori vaccine: mucosal adjuvant & delivery systems.
Vaccination, especially mucosal vaccination, is considered to be effective in the management of Helicobacter pylori infections. However, most antigens alone cannot induce immune responses when administered mucosally and need to be co-administered with adjuvants or delivery systems. The current research on the mucosal adjuvant and delivery systems of vaccine against H. pylori, including advantag...
متن کاملHelicobacter pylori: Eradication or Preservation
Helicobacter pylori infects about 50% of the world's population and inevitably results in the development of gastritis. Of those infected, about 10% develop peptic ulcer disease and roughly 1% develop gastric cancer. Conversely, some take the view that H. pylori infection provides some protection against gastro-esophageal reflux disease and possibly asthma. This review aims to explore the case ...
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عنوان ژورنال
دوره 4 شماره 3
صفحات 1- 2
تاریخ انتشار 2016-08
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